Dextran sulfate is a polyanionic derivative of dextran
produced by esterification of Dextran with chlorosulphonic acid. Dextran
sulfate sodium (DSS) is the sodium salt which is a white to off-white powder
freely soluble in water and salt solutions to form a stable, clear solution.
The sulfur content is approximately 17% which corresponds to an average of
1.9 sulfate groups per glucosyl residue of the dextran molecule. Dextran is a
polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166)
linkages. The remaining (163) linkages account for the branching of dextran.
Applications
Dextran
Sulfate Sodium (DSS) which has proven to have versatile value in
Biomedical/clinical research. DSS can be used to study Colitis (Inflammatory
Bowel disease) as well as an antiviral as agent.
Inflammatory Bowel Disease (IBD) is characterized by chronic and relapsing
inflammation of the gastrointestinal tract which is associated with increased
risk of developing colitis-associated cancer. Several animal models have been
used to study colitis and one such model involves the oral administration of
dextran sodium sulfate (DSS) in the drinking water of mice leading to chronic
colitis. This DSS induced colitis model is spontaneous and is used to assess
the therapeutic potential of treatments for IBD.
Bamba et al (2012) performed a comparative analysis of 3 different DSS
preparations to examine the chemical and cytotoxic properties as well as
severity of colitis. Their study concluded that the DSS from MP Biomedicals
induced a severe colitis as indicated by body weight transition, DAI score,
colon weight/length and histological scores. This DSS is well characterized
and offers the following advantages:
• Highest sulfur content – 19%
• Highest chirality - +104° of specific rotation
• Lowest pH – 6.2 at 1% solution
Order Information
Cat#
Description
Pack Size
Remark
0216011001
DEXTRAN SULFATE
SODIUM SALT (36,000-50,000 M.Wt.) Colitis Grade
1g
0216011010
DEXTRAN SULFATE SODIUM SALT
(36,000-50,000 M.Wt.) Colitis Grade
10g
0216011025
DEXTRAN SULFATE
SODIUM SALT (36,000-50,000 M.Wt.) Colitis Grade
25g
0216011050
DEXTRAN SULFATE SODIUM SALT
(36,000-50,000 M.Wt.) Colitis Grade
50g
0216011080
DEXTRAN SULFATE
SODIUM SALT (36,000-50,000 M.Wt.) Colitis Grade
100g
Best
0216011090
DEXTRAN SULFATE SODIUM SALT
(36,000-50,000 M.Wt.) Colitis Grade
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Shipping
Shipping Method : Parcel Service
Shipping Area : A Region.
Shipping Cost : International Shipping Fee
Shipping Time : 3 - 7 days
Please take into consideration that some products may take additional time for delivery and processing. Important: Your order is shipped once your payment has been cleared. Please contact our customer service center if you would like to request an exchange or return on your order.
- Customs and Duties
The recipient will be held responsible for international shipments which may be subject to import duties and taxes. Please be advised that these charges are levied by the destination country and we do not have control over them. In the case that the recipient refuses to receive the parcel, the order will be returned to Korea and will not be re-shipped. Relevant expenses (round-trip shipping, customs, etc.) will be deducted from the refund.
Returns & Exchanges
1. Requirements:
Please take into consideration that we only accept qualifying returns but not exchanges. Refunds are issued once the returned products clear our inspection.
1) An item is eligible for cancellation if: -you posted a Return request within 24 hours of payment and your order is still under “Pending” status (if your order is under “Preparing Shipment” status, please contact our customer service center) or -the order is delayed for more than 10 days since payment and you have not received any notification regarding the delay; or -the ordered item is out of stock.
2) We accept return(s) if:
-you receive a product different from your order; or
-you receive a defective product.
**Return Instructions
(1) Post a return request on our Return forum within three days of receipt. You are required to attach the photos of the received product(s) and include the item code, the order number, and the reason for the return.
(2) A customer service representative will be in contact to assist you by email or phone.
(3) Items returned must be in their original condition, which includes tags and any packaging. Also, you need to include a note of your order number, name, and user ID.
*Please be advised that returns are accepted ONLY IF you followed the instructions above and your return request has been approved by our staff. Returns that are shipped to us without any prior consent are not accepted.
*Please note that EVEN the defective/incorrect item(s) must be returned with all of the tags and labels intact. The item(s) must be sent in their original packaging and unworn.
*Please include all contents of the original package and free gifts (if applicable) in your return packaging.
* Shipping fee for any return caused by our fault will be paid by the company. However, if EMS’ cash on delivery is not possible then you can scan the return receipt and either mail it with the item to return or post an image of it on the forum. The shipping fee will be refunded once the returned item has arrived.
3) We do not accept return(s) if:
-you are returning the items just because you changed your mind (on size, color, etc.) -you are returning shoes, bags, or any other accessories -the products are damaged due to your mishandling -your return request is not approved by our staff
The following items are not considered defective:
* Items that are originally manufactured without tags or labels * Items with creases that may have been made while shipping * Items with unsatisfactory/incomplete finish due to mass production
4) If there is a missing item from your order:
*Contact our customer service center by phone or by forum (if you cannot reach us by phone) within 1 day of delivery. *Please keep all contents of the original package including packaging material (boxes, plastic bags etc.) with you until you are instructed otherwise.
Please note that we may not be able to process the refund for your missing item if you lose or damage any packaging material.